Compliance

HITRUST CSF,explained

6 min read · Updated June 2026

HITRUST CSF is a certifiable security framework, widely used in US healthcare, that harmonises HIPAA, ISO 27001, NIST, and other standards into one prescriptive control set. It is often requested because a HITRUST certification gives independent assurance that HIPAA-relevant controls are genuinely in place.

What HITRUST is

The HITRUST CSF (Common Security Framework) takes many standards and regulations and maps them into a single, prescriptive set of controls. Instead of separately interpreting HIPAA, ISO 27001, and NIST, an organisation works one harmonised framework that draws on all of them.

It is most established in US healthcare, where covered entities and their vendors use a HITRUST certification as a recognised way to demonstrate a strong security posture.

How it relates to HIPAA

HIPAA is the law and sets the obligations; HITRUST is a framework that operationalises and certifies them alongside other standards. HIPAA itself has no certificate, so healthcare buyers often ask for HITRUST certification as independent evidence that HIPAA-relevant controls are in place and tested.

Assessment types

HITRUST offers tiered assessments so the rigour matches the need:

  • A lower-effort assessment for a basic, foundational level of assurance.
  • An intermediate assessment for moderate assurance.
  • A validated assessment, the higher-assurance option, performed with an authorised external assessor and leading to HITRUST certification.

Who uses it

Healthcare providers, health plans, and the technology vendors that serve them. Because handling protected health information carries real risk, a HITRUST certification is a common requirement in healthcare procurement and vendor due diligence.

How to approach it

  1. 1Scope the systems and information, including any handling of PHI.
  2. 2Choose the assessment type that matches the assurance your buyers expect.
  3. 3Implement the HITRUST controls and gather evidence.
  4. 4Work with an authorised external assessor for a validated assessment.
  5. 5Reuse overlapping ISO 27001, SOC 2, and HIPAA work rather than starting again.

Frequently asked questions

What is the difference between HIPAA and HITRUST?

HIPAA is US law and sets the obligations for protecting health information; it has no certificate. HITRUST CSF is a certifiable framework that operationalises HIPAA alongside ISO, NIST, and other standards, so a HITRUST certification gives independent assurance that the relevant controls are in place.

Who issues a HITRUST certification?

A HITRUST validated assessment is performed with an authorised external assessor, and HITRUST issues the certification. Tooling can prepare and maintain the programme, but it does not issue the certification itself.

Who needs HITRUST?

Mostly healthcare organisations and the technology vendors that handle protected health information on their behalf, where a HITRUST certification is frequently requested during procurement and vendor due diligence.

Do this in a fraction of the time

Diligio centralises your approved answers, drafts each response grounded in your sources, and independently verifies it before you review. RFPs, DDQs, and security questionnaires, answered from one knowledge base.

Related guides

Due diligence

What is a DDQ (due-diligence questionnaire)?

Due diligence

DDQ vs RFP: what is the difference?

RFPs

RFP vs RFI vs RFQ: what is the difference?

RFPs

The RFP response process: a step-by-step guide

RFPs

How to build an RFP content library

RFPs

The bid/no-bid decision: when to respond to an RFP

Security questionnaires

How to respond to security questionnaires faster

Security questionnaires

SIG vs CAIQ vs VSAQ: the security questionnaires explained

Security questionnaires

Vendor security assessment checklist

Compliance

SOC 2 vs ISO 27001: what is the difference?

Compliance

ISO 27001 readiness checklist: how to prepare for certification

Compliance

SOC 2 for startups: a practical guide

Compliance

GDPR compliance for SaaS: a practical guide

Compliance

HIPAA compliance for software vendors

Compliance

PCI DSS compliance, explained

Compliance

The NIST Cybersecurity Framework, explained

Compliance

ISO 42001, the AI management standard, explained

Compliance

ISO 27017 and ISO 27018: cloud security and privacy, explained

Compliance

ISO 22301 and business continuity, explained

Compliance

DORA, explained

Compliance

Cyber Essentials, explained

Compliance

The CCPA and CPRA, explained

Compliance

NIST 800-53, explained

Compliance

NIST 800-171 and CMMC, explained

Compliance

FedRAMP, explained

Financial regulation

BSA/AML, explained

Financial regulation

The FATF 40 Recommendations, explained

Financial regulation

MiFID II and MAR, explained

Financial regulation

Consumer credit and fair lending, explained

Due diligence

Third-party risk management (TPRM): a practical guide

Putting HITRUST into practice? See Diligio Compliance for HITRUST.